A survey of modern biochemistry using case studies that highlight general theories and unifying concepts. This course is open to all majors and does not require any college science courses as background or prerequisite. Typically offered Fall Spring.

BCHM 10000 Introduction To Biochemistry

Introduction To Biochemistry

An entry-level laboratory course to help freshmen students become interested and excited about scientific research, and at the same time, gain the skills necessary to become better prepared for undergraduate research opportunities. Students perform real-world experiments to identify single base-pair changes in a DNA sequence that can change a protein-protein interaction. Students learn common laboratory skills such as pipetting, centrifugation, and sterile technique. Students also learn how to display and interpret scientific results in written form.

BCHM 10100 Introduction To Biochemistry Laboratory

Introduction To Biochemistry Laboratory

Discussion of qualitative and quantitative analysis of biological compounds including pH measurement and control, spectrophotometry, measurement of radioactivity; theoretical basis of various separation techniques, including chromatography and electrophoresis; application of these methods to separation and analysis of biological compounds. Laboratory sessions will provide practical experience in the use of these methods. This course is designed for biochemistry majors. Typically offered Fall Spring.

BCHM 22100 Analytical Biochemistry

Analytical Biochemistry

Introduction to fundamentals of scientific principles and practice in biochemistry.  Students will learn how to develop hypotheses, design experiments, and critically analyze results to create new knowledge.  Intended for sophomores.  Typically offered Spring.

BCHM 29000 Experimental Design Seminar

Experimental Design Seminar

Supervised individual research. This course is intended to provide an introduction to independent undergraduate research. The primary goal of this experience is to learn the mechanics of laboratory science. Students will learn to work in a real laboratory situation where experiments are not preassembled for them. Students will record their data in laboratory notebooks, and gain experience in trouble-shooting and critically analyzing the results of their experiments. Permission of instructor required.

BCHM 29800 Introduction To Biochemistry Research

Introduction To Biochemistry Research

Supervised individual research. Weeks 9-16. This course is intended to provide a brief introduction to independent undergraduate research. Students should plan on continuing their research in the same laboratory in the following semester. The primary goal of this course is to gain experience working side-by-side with researchers in a real laboratory setting. Students will begin to learn how to best record their data in laboratory notebooks, and gain experience in trouble-shooting and critically analyzing the results of their experiments. Permission of instructor required.

BCHM 29801 Head Start To Introductory Biochemistry Research

Head Start To Introductory Biochemistry Research

Students will have an understanding of the following content areas: structure/function of amino acids, carbohydrates, lipids and nucleic acids; protein structure, function and purification; basic enzymology; replication, transcription and translation; intermediary metabolism including glycolysis, the citric acid cycle, oxidative phosphorylation, photosynthesis.  Students will also develop an appreciation for some of the contributions that have been made by biochemistry to society, including improvements to medicine, agriculture, and the economy.  Typically offered Fall Spring Summer.

BCHM 30700 Biochemistry

Biochemistry

Experiments that introduce methods for analysis and separation of biological molecules and that illustrate the biochemical and metabolic concepts covered in BCHM 30700.

BCHM 30900 Biochemistry Laboratory

Biochemistry Laboratory

Modern biochemical techniques for the purification and characterization of biological proteins. This is a project-oriented course where students begin by purifying a recombinant enzyme by affinity chromatography and then characterize various biochemical properties of the enzyme throughout the semester. Emphasis will be placed on quantitative analyses, including measurements of enzyme activity and inhibition, molecular interactions, and oligomeric state. Students will learn basic principles of designing assays to measure biochemical phenomena. Use of bioinformatics and computational modeling tools for protein structure analysis will be integrated. The course will culminate with preparation of a manuscript-style report describing the enzyme characterization.

BCHM 32200 Analytical Biochemistry II

Analytical Biochemistry II

A lecture course that relates biochemistry to organic chemistry.  Chemical principles relevant to the assembly and function of macromolecules, the logic of biological free energy conversion, and enzyme catalysis are emphasized, all of which provide a foundation for the study of metabolism.  Typically offered Spring.

BCHM 36100 Molecules

Molecules

The objective of this course is to help biochemistry students with professional development and career planning. Students will learn about career possibilities, interview skills, job search strategies, graduate and professional school applications, resume construction and industrial practices. Intended for juniors.

BCHM 39000 Professional Development Seminar

Professional Development Seminar

Students will acquire, assess, clean, visualize and analyze biological data sets with R. Students will be able to describe the link between complex biological phenomena and the data captured through human observation or scientific instrumentation. Students will learn how to organize data sets to optimize clarity and analytic possibilities while minimizing errors with examples drawn from the literature or biological databases. R will be taught starting with small-scale data such as drug sensitivity assays moving to genome-scale analyses such as gene expression and pathway analysis later in the course. These skills will be taught in the light of increasing data literacy and enabling reproducible research through clear documentation of data and communication of analyses. Relevant concepts from biology and statistics will be reviewed. Typically offered Fall Spring.

BCHM 42100 R For Molecular Biosciences

R For Molecular Biosciences

This course introduces students to modern genomics and computational tools that will be used for screening. Students will review the notion of gene, genomic, transcriptome, and epigenome, and show how next generation sequencing technologies are utilized to measure these with cell.

BCHM 42200 Computational Genomics

Computational Genomics

This course applies the principles of biochemistry and metabolic regulation to understand the diagnosis and treatment of human disease. The course emphasizes the biochemistry relevant to diabetes, blood disorders and the medical consequences of liver disease and aging. Roughly half of the class time is focused on small group activities including team-based learning and problem-based learning using patient cases. Students will search authoritative sources to discover links between biochemistry and clinical symptoms and communicate that information to their peers. Typically offered Spring.

BCHM 43400 Medical Topics In Biochemistry

Medical Topics In Biochemistry

A lecture course to provide students with a broad and thorough understanding of core metabolic pathways and how they are resulted. Anabolic and catabolic processes of metabolic pathways will be studied at the biochemical, structural, genetic and molecular levels. Students will learn to appreciate how the various metabolic pathways are integrated and how the fundamental metabolic pathways relate to medicine, agriculture and human disease.

BCHM 46200 Metabolism

Metabolism

Major questions in biochemistry and contemporary approaches to these problems.  Material covered in class will primarily be derived from primary literature.  Students will continue to develop the skills needed to critically read, evaluate, and assimilate the primary scientific literature.  Typically offered Spring.

BCHM 46500 Biochemistry Of Life Processes

Biochemistry Of Life Processes

Discussion of individual student's research projects. Preparation of posters and public seminars based upon research results. Permission of instructor required. Typically offered Fall Spring.

BCHM 49000 Undergraduate Seminar

Undergraduate Seminar

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BCHM 49500 Computational Genomics

Special work in biochemistry not included in other courses. Permission of instructor required. Typically offered Fall Spring Summer.

BCHM 49500 Comparative Genomics

Comparative Genomics

BCHM 49500 R For Molecular Biosciences

Supervised individual research. This course is intended to provide the opportunity for in-depth, independent undergraduate research. The students enrolled in this course will learn how to devise hypotheses, design experiments that test their hypotheses, record their data in laboratory notebooks, critically analyze the results of their analyses, and present their findings to others in written form. Permission of instructor required.

BCHM 49800 Research In Biochemistry

Research In Biochemistry

Supervised individual research. Weeks 9-16. This course is intended to provide a brief research experience in preparation for in-depth, independent undergraduate research the following semester. The students enrolled in this course will begin to learn how to devise hypotheses, design experiments that test their hypotheses, record their data in laboratory notebooks, critically analyze the results of their analyses, and present their findings to others in written form. Permission of instructor required.

BCHM 49801 Head Start To Biochemistry Research

Head Start To Biochemistry Research

This course is intended to provide the opportunity for in-depth, independent undergraduate research. The students enrolled in this course will learn how to devise hypotheses, design experiments that test their hypotheses, record their data in laboratory notebooks, critically analyze the results of their analyses, and present their findings to others in the form of a written thesis. Permission of instructor required.

BCHM 49900 Honors Thesis In Biochemistry

Honors Thesis In Biochemistry

The course provides an understanding of the forces that act on genome content and organization, and the ability to interpret genetic variation between genomes. Students will acquire skills to utilize public genome databases, visualize genomic regions/features of interest using a genome browser, and perform phylogenetic analysis. The knowledge gained is central within the fields of genetics, bioinformatics, microbiology, and evolutionary biology and have important applications in numerous related fields including medicine, biotechnology, agriculture, and ecology. Typically offered Spring.

BCHM 52100 Comparative Genomics

(BIOL 53601) This course is aimed at expanding students' fundamental interests in biology, chemistry and biochemistry to how drugs work. The course will provide an overview of the modern day drug discovery pipeline and an in-depth look at the basic biology, structure, and mechanisms-of-action behind marketed therapeutics. The course will start with a historical account of the discovery of natural product drugs such as aspirin and penicillin and will then venture into the modern day era of drug discovery including structure-based drug design. We will explore different classes of antibiotics, antiviral, and anti-cancer drugs and their targets including small molecule drugs and modern biologics-based drugs.

BCHM 53600 Biological And  Structural Aspects Of Drug Design And Action

Biological And  Structural Aspects Of Drug Design And Action

This course provides upper-division undergraduate and graduate students with basic understanding of biochemical and structural properties of amino acids, nucleic acids, lipids, and carbohydrates. This course allows students to connect the relationship between structure and function of biomolecules. In addition, students learn to understand enzyme properties, enzyme mechanism of action, and enzyme regulation.

BCHM 56100 General Biochemistry I

General Biochemistry I

This course provides upper-division undergraduate and graduate students with an understanding of core metabolic pathways.  Anabolic and catabolic processes of metabolic pathways are studied.  Biochemical and structural knowledge is used to determine how enzymes and coenzymes are needed to regulate and control metabolic pathways.  Typically offered Spring.

BCHM 56200 General Biochemistry II

General Biochemistry II

The objective of this course is to assist students in acquiring the skills needed to read critically, evaluate, and assimilate the primary scientific literature. This objective will be accomplished by instructor-guided discussions of the hypotheses, experimental data, conclusions, and scientific merit of assigned manuscript(s) taken from the fields of biochemistry and molecular biology. Topics for discussion initially will focus on the structure, organization, review process, and ethical issues related to scientific manuscripts. As the semester progresses, discussions will focus on the hypotheses being tested, quality of the data, and validity of the conclusions. Permission of instructor required.

BCHM 60100 Critical Thinking And Communication In Biochemistry I

Critical Thinking And Communication In Biochemistry I

The objective of this course is to assist students in acquiring the skills needed to read critically, evaluate, and assimilate the primary scientific literature. This objective will be accomplished by instructor-guided discussions of the hypotheses, experimental data, conclusions, and scientific merit of assigned manuscript(s) taken from the fields of biochemistry and molecular biology. Topics for discussion initially will focus on the structure, organization, review process, and ethical issues related to scientific manuscripts. As the semester progresses, discussions will focus on the hypotheses being tested, quality of the data, and validity of the conclusions. Permission of instructor required. Typically offered Fall.

BCHM 60100 Critical Analysis Of Biochemical Research Literature I

Critical Analysis Of Biochemical Research Literature I

Builds on the skills developed in BCHM 601. Students will continue to enhance their analytical skills, and class discussions will be conducted at a more sophisticated level and will go into greater depth. Class discussions will focus more on the analysis and evaluation of current methodologies and hypotheses in the biochemical and molecular biological literature. Students will be evaluated primarily on their preparation and participation in each class discussion.  Prerequisite: BCHM 60100. Permission of instructor required. Typically offered Spring.

BCHM 60200 Critical Analysis Of Biochemical Research Literature II

Critical Analysis Of Biochemical Research Literature II

BCHM 60200 Critical Thinking And Communication In Biochemistry II

Critical Thinking And Communication In Biochemistry II

This course is intended to provide the opportunity for in-depth, mentored graduate research in two biochemistry laboratories. Students enrolled in this course will learn how to devise hypothesis, design experiments that test their hypotheses, accurately record their data in laboratory notebooks, critically analyze the results of their analyses and present their findings to others in written and oral presentations. They will fully participate in laboratory group meetings, the Biochemistry seminar series, and presentations by other students and postdoctoral fellow. Co-requisites: BCHM 60100 and BCHM 60501. Permission of department required.

BCHM 60300 Introduction To Graduate Research In Biochemistry I

Introduction To Graduate Research In Biochemistry I

This course builds upon BCHM 60300 to provide continued opportunity for in-depth, mentored graduate research in one biochemistry laboratory. Students enrolled in this course will learn how to devise hypothesis, design experiments that test their hypotheses, accurately record their data in laboratory notebooks, critically analyze the results of their analyses and present their findings to others in written and oral presentations. They will fully participate in laboratory group meetings, the Biochemistry seminar series, and presentations by other students and postdoctoral fellows. Co-requisite: BCHM 60200 and Pre-requisites: BCHM 60300 and BCHM 60501. Permission of department required.

BCHM 60400 Introduction To Graduate Research In Biochemistry II

Introduction To Graduate Research In Biochemistry II

This course will provide students with an understanding of the basic principles that underlie the secondary and tertiary structure of proteins and nucleic acids which contribute to their function. It will inform students of current efforts to engineer macromolecules with novel functions. Students will become familiar with methods used to determine the three-dimensional structures of macromolecules, and they will learn to critically evaluate the accuracy of structural models. Special topics in the current literature, including membrane proteins, drug design and ribozymes, will be covered. The class will typically include students from a variety of departments, graduate programs, and scientific backgrounds. The course will be taught primarily from various textbook and from the primary literature. A biochemistry course designated for majors is a prerequisite of the course. Lack of the prerequisite will require approval of the instructor. Permission of Department required.

BCHM 60501 Macromolecules

Macromolecules

This course will provide students with a basic understanding of gene expression mechanisms with a s specific focus on newly emerging topics.  This course will be taught from current primary literature, using a textbook as a background resource.  Topics will include transcription, messenger RNA decay, microRNAs and connections between gene expression steps.  Students will learn how to read and interpret scientific literature through class presentations, discussions and take home assignments.  Additionally, students will gain experience in developing and testing hypotheses within the class topic areas and writing a research proposal.  Prerequisites: BCHM 56100 and 56200, or BCHM 60501.  Lack of these prerequisites will require approval by the instructor.  Typically offered Spring.

BCHM 61000 Regulation Of Eukaryotic Gene Expression

Regulation Of Eukaryotic Gene Expression

This course provides a hands-on experience for life science researchers in the bioinformatic analysis of genome-scale data. The various disciplines in the life sciences are generating a wealth of experimental and annotation data. Today's graduate students need experience with modern tools that can help them to access, explore, analyze, interpret and manage the data that they generate in the lab. Students will use the R programming language and packages from Bioconductor, the R bioinformatics project, as their principal tools for this course. Students will develop workflows in R that bridge established algorithms for bioinformatics such as limma, edgeR or DESeq2, incorporating methods to import, QC, transform and visualize genome-scale datasets derived from next generation sequencing experiments. A critical aspect of bioinformatics that is often inadequate is workflow documentation. This course will use Rmarkdown to integrate computer code, data and results to manage complex bioinformatics projects. The class has lecture, lab and distance components. Lectures will focus on the theoretical and biological aspects of bioinformatics analysis using recent examples from the literature. In lab, students will work on programming exercises or projects using published datasets. Advanced students will also have the opportunity to work with their own data. Distance instruction will include R tutorials and videos that students can work through at their own pace (subject to completion deadlines). Particular emphasis will be placed on the theoretical and practical limitations of next generation sequencing data. No prior computer programming experience is required, but it is assumed that students have a firm grasp of the fundamental principles of molecular biology and how they relate to complex processes such as gene expression and genome organization. Permission of instructor required.

BCHM 61200 Bioinformatic Analysis Of Genome Scale Data

Bioinformatic Analysis Of Genome Scale Data

The goals of this course are to introduce students to 1) basic principles of mass spectrometry, 2) the most common instruments used for protein mass spectrometry including the advantages and disadvantages of each, 3) the most common applications of protein mass spectrometry in biological research, 4) current approaches to quantitative protein mass spectrometry and their use in proteomic studies 5) the skills necessary to analyze mass spec data from a variety of experiment types including the ability to use and understand common database search programs, and 6) contemporary issues associated with large-scale proteomics experiments (including technical challenges and limitations) culminating in the ability to design appropriate experiments to answer a specific proteomic question.  Prerequisite: Students need to have taken an undergraduate level biochemistry course and be familiar with basic aspects of protein structure that are taught in such courses. In the absence of an undergraduate biochemistry course, students should discuss their qualifications with the instructor before registering.  Typically offered Spring.

BCHM 62000 Protein Mass Spectrometry And Proteomics

Protein Mass Spectrometry And Proteomics

(AGRY 64000, BIOL 64000, BTNY 64000, HORT 64000)  Topics include photosynthesis, respiration, carbohydrate and lipid metabolism, and nitrogen, sulfur, and secondary metabolism. This course is the third in a series of core courses in the Purdue Plant Biology Program graduate curriculum. Prerequisite: BCHM 56100, BTNY 55300 or HORT 55300, Prerequisite: BIOL 55100 or HORT 55100.

BCHM Courses

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BCHM Courses

.css-1o363pe{width:var(--chakra-sizes-4);height:var(--chakra-sizes-4);}BoilerClassesis an unofficial catalog for Purdue courses made by Purdue students, based in West Lafayette, Indiana. We'd love to hear your feedback!

BoilerClassesis an unofficial catalog for Purdue courses made by Purdue students,
based in West Lafayette, Indiana. We'd love to hear your feedback!